Filtration For Pharmaceutical Applicationjtrooz.com/Catalog/Membrane.pdf · pressure drop, which...
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Filtration For Pharmaceutical Application
Transcript of Filtration For Pharmaceutical Applicationjtrooz.com/Catalog/Membrane.pdf · pressure drop, which...
Filtration For Pharmaceutical Application
Contents
Introduction
Application
Filtration Range
Particle 10-4 10-3 10-2 10-1 1.0 10 102 103
( μm)
Average Molecular 100 200 20,000 500,000
Fabric Filtration
Mesh
Micro-Filtration
Ultra-Filtration
NF
RO
Filtration Range
Red Blood Cell
Emulsion
Oil Emu
Paint Pigments
Bacterial Sand
Hair Protein, Enzyme
Carbon Granules
Virus
Radiating Atom
Soluble Pigments
VOC, PCD, Susp. Oil
Metal Ion
Membrane
Type
Pore Size
weight
Micro Filtration
Wound String Filter
Melt Blown Filter
Activated Carton Filter
Pleated Cartridge Filter
Filter Bag
….
Filtration of Pharmaceuticals
Gas Filter
API Filter
Buffer Filter
Injection Filter
Serum Filter
Gas Filtration Process
Oil and Water Remove System
Sterile
Filtration Sterile
Filtration
Pre-Filtration
Vent
Vapour
Stainless Steel Filter
Fermenter Container sterile
CF sterile
Product Sterile
Pre-Filtration（0.01umGF）
Sterile Filtration（0.01umPTFE）
Stainless Steel Filtration（2um）
API Filtration Process
Pre-Filtration(0.45um)
Sterile Filtration（0.22um）
Buffer Filtration Process
Tank Pre-Filtration Sterile
Filtration
Storage
Tank Analysis
Pre-Filtration(0.45um)
Sterile Filtration（0.22um）
Injection Filtration Process
Titanium stick filter （1um）、Pre-Filtration（1umPP pl
eated）
2 level Pre-filtration（0.45umPES、0.45umPVDF）
Sterile Filtration（0.22umPES 、0.45um PVDF）
Serum Filtration Process
Clarification Filtration（5um）
Pre-Filtration（0.45um）
Sterile Filtration（0.22um, 0.1um）
Conclusion
For Pharmaceutical application, our cartridge filter can b
e used as Pre-Filtration System, Sterile Filtration and G
as Filtration.
Any more information needed, please feel free to contact
me at any time.
MaterialDiameter/mmFeatures
*We still offer MCE customized membrane etc.
MS® sample vials
2mL Autosampler Vials for HPLC
8-425/9-425/10-425/Crimp top/Snap top
2mL Dimension 32*11.6mm
Type I, 33 expansion glass(Clear)
Type I, 51 expansion glass(Amber)
Assembled Caps and Septa for 2mL Autosa-mpler Vials
Design of the Neck
Material
Septa
8-425/9-425/10-425 Crimp top/ Snap top
Polyethylene AluminumPolyethylene
1.Pre-slit Blue PTFE/White Silicone Septa2.Red PTFE/White Silicone Septa3. White PTFE/Red Silicone Septa
Design of the Neck
Volume
Type of Glass
Dimension
24-400
20/30/40mL
Type I, 33 expansion glass(Clear)Type I, 51 expansion glass(Amber)
57*27.5/72.5*27.595*27.5
Assembled Caps and Septa for Storage Vials
Design of the NeckMaterialSepta
24-400PE, center hole/PE, closed topWhite PTFE/Nature Silicone Septa
MS Advantage
Contact Us
About us
Headspace Vials
Caps and Septas for Headspace vials
Screw Vials for Storage
01
About MS
02
Manufacturing& Laboratories
03
Research & Development
04
Products
05
What Can We Do
Contents
Ⅰ. About MS - General Information
Location: Headquarter in WA, USA
Employees: about 250
Main Business Scope: Membrane & Filter
Started Business: 2006 USA; 2008 China
Plants: R&D Center: Office:
1) Seattle, WA, USA Nantong, Jiangsu, China Seattle, WA, USA
2) Nantong, Jiangsu, China Shanghai, China Tokyo, Japan
3) Chongqing, China Wuhan, Hubei, China Wuhan, Hubei, China
Shanghai
Ⅰ. About MS - General Information
2006.06: Founded Membrane Solutions USA
2007.08: Imported German Brand Membrane for
domestic Market in USA & China
2008.02: Founded New and the 1st Plant in Nantong
2009.03: ISO 9001 Certified
2009.06: Manufacturing Lab Filtration Products
2010.08: Manufacturing Industry Filtration Products
2011.06: First Flat Sheet Microfiltration Nylon
2011.09: CE Certified
2013.06: FDA Registered
2014.12: 60M Syringe Filters, #1 in the world
2014.12: OEM for Top 5 account in the world
2015.12: Start Assembly in USA
History
2009 2011 2013
轻 点 此 处 输入文字内容
20152010 2012 2014 20162006
MS was Founded in MA, USA
2009
ISO9001 and Lab Products
2013
FDA Registered and Residential Products
2015
Start Assembly in USA
2008
China 1st Plant in Nantong
2011
CE Certified and Industry Products
2014
60M Syringe Filters, #1 in the world
2016
Ⅰ. About MS - Organization
MS (USA)
MS(USA)
MS(China)
MS(USA)
MS(China)
MS(Japan)
R&D, Tech support
Operational& Support
Sales Dept.
Manufacturing
Ⅰ. About MS - Certificates
Ⅰ. About MS – Sales/Marketing and R&D
R&D:
• Core Technology – Air & Liquid Filter Membrane
• Filtration cover microfiltration-
ultrafiltration- Reverse Osmosis (RO)
• Continual new products and application
development
• Lab-to-Industry Application Establishment
Sales & Marketing:
• Marketing Segment
• Sole Distributor
• Special OEM team
• Dot to Dot training, SOP training
• More than 20 trade show every year
• E- business ( Amazon & E-bay)
Ⅰ. About MS – Global Warehouse & Sales Network
Europe Spain & Italy
ChinaUSA, Ohio & Dallas
South America : Brazil
Oceania
Africa
Ⅱ. Manufacturing & Laboratories
Class 100,000 clean room QC Laboratory in Nantong
Manufacturing in Nantong
Ⅱ. Manufacturing & Laboratories
Validation Laboratory in Shanghai Application Laboratory in Wuhan
Ⅲ. Research and Development
Microfiltration membrane
PES HydrophilicFast Flow
PVDFHydrophobicHydrophilic
PTFEHydrophobicHydrophilic
NylonHydrophilic
Ultrafiltration membrane
PVDFHydrophilic
PVDFHydrophilicNY Supported
PES Hydrophilic
Reverse Osmosis membrane
Ⅲ. Research and Development - Instruments
Ⅳ. Products Family
Lab Filtration
请输入标题
• HPLC Syringe Filter
• Sterilized Syringe Filter
• 50mm Venting Filter
• Gridded Membrane Filter
• Disc Membrane Filter
• Blotting Membrane
• Sample Vial
• SPE Column
• Ultrapure Water System
• RO Membrane
• Pure Water System
• UF Residential Membrane
• Water Pitcher
• Life Straw
• POE Water Filter
• Micro-filtration membrane
• UF membrane
• RO Membrane
• Cartridge Filter
• MBR Skid System
• Ultra-pure Water system
Lab Filtration Residential Industry
Ⅳ. Products – Lab Filtration
Membrane Selection Guide
Φ4mm Φ50mm
Syringe Filter
Ⅳ. Products – Lab Filtration
Allpure
Simplepure
Chrompure
Φ13mm Φ25mm
Superpure
Bepure
Biopure
Φ17mm Φ30mm Φ33mm
Ⅳ. Products – Lab Filtration
2ml Sample Vial
HeadSpace Vial
Micro-Sampling Vial & inserts
Storage Vial
Ⅳ. Products – Lab Filtration
MCE Gridded Membrane Filter
White gridded membranes are designed for General Purpose
Examination of all microorganisms, the recovery and retention
of E. Coli bacteria in water/wastewater analysis as well as
other microbiological tests.
Black MCE are available plain for automatic colony counting
applications, as well as gridded to assist in manual counting
procedures, analysis of yeast and mold.
Ⅳ. Products – Industry Filtration
Depth Filter （Standard & Non Standard ）
String Wound Melt Blown PP Pleated GF Pleated PE Pleated Activated carbon filter
Membrane Pleated Filter （Standard & Non Standard）
PES Pleated
NY Pleated
PTFE Pleated
PVDF Pleated
UPE Pleated
PSPleated
MCE Pleated
Cartridge filter
Ⅳ. Products – Industry Filtration
Ultra-filtration membrane & Module
Ⅴ. What Can We Do
n Facility Background
State-of-art welding
technology
Exclusive OEM Service
Automatic Production
High Quality and Stable Products Wide Application Complete
Production Line
n Friendly Choice
Four Steps QC High Throughput /Flow rate COA Delivery
n Quality Control
STAY PURE
Bag Material
Filter Material
Size/mm
Pore Size/μm
PES/PTFE/PP/Nylon/MCE
0.1/0.22/0.45/1/3/5
Φ67X90; Φ67X112Φ65X46; Φ75X165
Size/mm
Pore Size/um
Temperature/F
Features
Application
Picture
PP/PE Needled Felt/Melt Blown
1/3/5/10/25/50/100
200/300
25/50/100/150/200/250/300
275
#01:Φ180*420 L ; #2: Φ180*810 L#3: Φ102*230 L; #4: Φ102*380 L
Nylon monofilament mesh
100% PP/PE, melt blown; welded seam construction; PP seal/stainless steel ring; low pressure drop
Prefiltering before membrane, Automotive coatings, chemicals, resins, edible oils and other fluid applications
Application: purification for various chemical material and medicaments; filtration for high additional liquid, small flux liquid and precious metal; filtration for strong corrosive solvent and gas filtration; filtration for pharmaceutical industry, chemical industry and biotechnology.
Features-HOSEBARE/MNPT; PP housing; Each filter experiences 100% integrity test; Thermal bonding; different pore size
Sewn/weld seam construction; PP seal/stainless steel ring; uneasy to be deformed, high tensile strength; good stability
Prefiltering, filtration for automobile degreasing, raw water filtration, coarse filtration, circulating water filtration
Membrane Solutions is a filtration company focuses on advanced membrane technology. People-oriented principle, qualified filtration products, excellent management concept and sales mode are highly appreciated by MS, who is devoted in improvement of developing filtration field. MS has moved into China since 2005, And now, with a plant and a R&D base in Nantong, three sales branches in Nantong, Shanghai, Wuhan, respectively, MS starts its aggressively developing strategy in Chinese filtration field. In 2010, HQ from Texas, America further reinforced investment in China, which means China becomes an important part of MS global development. According to perfect different walks of life. At present, MS products are widely applied in highly developed market, such as electronic and medical purification field, civil and industrial and municipal water treatment, etc.
MS will continue to make effort in solving and challenging difficulties in water treatment on the basis of sustainable development. We will make our social contribution through satisfying customer’s requirement on clean water, high energy efficiency, and environmental protection.
ISO 9001 Certification & CE MarketCertificate of FDA Registration Global Supply Chain and Efficient Customer Service Glass 100,000 clean Room Quick Delivery 5-7 days guaranteed OEM option, Private Labeling Service Consistent QA and Stable Product Supply
Filter Bag
Capsule Filter
Toll free: 1-214-775-2940Fax:732-412-4040Address:JP Morgan International Plaza Suite 650, 14241 Dallas Parkway, Dallas, TX，USWebsite:www.membrane-solutions.com
Tel: 0086-21-61478117Fax:0086-21-51687551Adress:2202, No.1759 North Zhongshan Road, ShanghaiWebsite:www.membrane-solutions.com
USA
China
Inquiry
Toll free: 0066-33-800658Adress:Suite #504,1-19-2 Nihonbashi, kakigaracho,chou-ku,Tokyo 103-0014
Please write to [email protected]
Online order
Please write to [email protected]
Japan
Contact Us
About Us
MS Features
Material
Length (inch)
Core
Micron Rating(μm) 0.5/1/5/10/20/30
DOE/SOE/Flat/Fin/222/226
AquaPure Classic Series
PP/CT
10/20/30/40
PP/Stainless Steel
Connection Type
MS String Wound cartridge filter is a kind of deep filter cartridge, which is made of the textile fabric string(Polypropylene, absorbentcotton and so on) previously winding onto the multi-hole axies according to the specific technology. The double O-ring sealing system ensures positive sealing of the filter cartridge within the filter housing and virtually eliminates and potential for bypass. The all polypropylene construction provides excellent compatibility in a wide variety of process streams.
Material
Length (inch)
Core
Micron Rating(μm) 0.22/5
Silicon/EPDM/Viton/NBR
Polypropylene
10/20/30/40/50/60
DOE/SOE/Flat/Fin/222/226
Seal material
MS Polypure-AB Absolute PP pleated Cartridge Filter uses the raw materials which have permitted by FDACR21. This type of cartridge tolerates a variety of chemical solvents, used in the filtration of ordinary or corrosive fluid. Application---Food and Beverage Processing, High Purity Chemicals, RO Pretreatment β≥1000Filtration Efficiency: ≥99%
Material
Length (inch)
Outside Diameter(mm)
Micron Rating(μm) 1//5/10
28mm, 30mm
Bituminous and coconut shell carbon
5/10/20/30
63mm/115mm Inside Diameter(mm)
MS ActivatePure CTO series carbon filter cartridge is shaped by extruding the premium grade activated carbon with food grade additives continuously, no release of carbon fines. The extrusion process allows more carbon, but a lower pressure drop, which enables the filter to deliver extended life while removing sediment, chlorine, taste, odor and organic contaminants from water, aqueous solutions or suspensions effectively. Application:Drinking Water, Swimming Pool, Chemical & petrochemical industry
Material
Length (inch)
Outside Diameter(mm)
Micron Rating(μm) 5/10
28mm
PAC impregnated cellulose
5/10/20/30
58mm/112mm Inside Diameter(mm)
MS carbon impregnated cellulose cartridge offer an economically solutions for general-purpose water filtration needs. The special filter media combine the benefits of both the sediment filter and the carbon block into a single cartridge with its outside fiber media removing sediments and the powdered activated carbon on the filter matrix absorbing chlorine, odor, taste, voc, organic chemicals etc.
MS Item
CRSP-3060
CRSP-3061
CRSP-3077
OD
2 3/4
2 3/4
4 1/4
9 3/4
9 3/4
4
1 1/16
1 1/16
1 15/16
1 1/16
1 1/16
1 15/16
Length Top Bottom
MS KleenPure replacement filter is used in the swimming pool and spa, various types can be manufactured by us and we could also satisfy all the requirements of your custom sizes. The cleaness and your health start from here. All KleenPure filter are manufactured using the best materials possible. MS designs and builds the highest quality and most sufficient pool and spa filters in the world.
Material
Length (inch)
Core
Micron Rating(μm) 0.22/0.45/1.0/5.0
Silicon/EPDM/Viton/NBR
Polyether-sulfone
10/20/30/40/50/60
DOE/SOE/Flat/Fin/222/226
Seal material
MS SteriPure Series pleated cartridge are manufactured with advance hydrophilic asymmetric polyetheure-sulfone membranes and all polypropylene components. The low protein binding nature of the filter membrane ensures suitability in many critical applications. The PES membrane provides accurate particle cut-offs and is compatible with a broad range of chemicals.
Material
Length (inch)
Core
Micron Rating(μm) 0.22/0.45/1.0/5.0
Silicon/EPDM/Viton/NBR
Polyether-sulfone
10/20/30/40/50/60
DOE/SOE/Flat/Fin/222/226
Seal material
MS Fluorpure cartridge filter uses a natural hydrophobic PTFE membrane along with non-woven support that provide an economical alternative to all fluorine media cartridges. All non-PTFE components utilizes high density polyethylene to ensure exceptionally low organic and metal ion extractables.
Excellent liquid and gas flow rates;100% integrity tested in cleanroom environment
Material
Length (inch)
Connection Type
Micron Rating(μm) 0.5/1/5/10/20/30
CRMPP0400500
MicroPure Classic Series
PP
10/20/30/40
DOE/SOE/Flat/Fin/222/226
Order Eg
MS MicroPure Classic Series is pure polypropylene depth filter, which offers better protection of RO membrane system.
Features: Graded pore structure enhances Dirt holding capacity; All PP construction provides good resistance to both organic and inorganic solvent; High contaminant removal efficiency; PP core provides excellent strength of cartridge filter; Long service life. Application: Pre-RO, Electronic Chemical Solvents; Drinking Water Treatment, Cooling Water
Material
Length (inch)
Connection Type
Micron Rating(μm) 0.1/0.22/0.45/1/5/10
Silicon/EPDM/Viton/NBR
PolyPure Classic Series
Polypropylene
10/20/30/40/50/60/70
DOE/SOE/Flat/Fin/222/226
Seal material
MS PolyPure Classic Cartridge Filer is constructed of micro polypropylene media and nonwoven or silk net support and is ideally suited for the removal of agglomerated particles and gels. Deep, wide pleats for long service life in liquids with high levels of suspended solids and designed for reverse flow cleaning and construction optimized for consistent performance under variation in flow.
Application: Food and beverage, Chemical industry, oil industry Filtration Area: 0.65 m2.
String Wound Cartridge Filter AB Absolute Pleated Filter ActivePure CTO Series
ActivePure CIC Series
KleenPure Replacement Filter Cartridge
SteriPure PES Cartridge Filter
FluorPure PTFE Cartridge Filter
Melt Blown Cartridge Filter
Pleated Cartridge Filter
Ref.MKT2-303
MS PolyPure Classic Filters offer economical solutions for a variety of requirements with its excellent filtration efficiency and chemical compatibility across a wide range of liquid process applications. The filter is constructed of pleated polypropylene filter media with high surface area which allows for greater system flow rate. The construction utilizes thermal welding techniques to seal all components and therefore eliminates extracts and optimizing cartridge
Testing was conducted using the single-pass test method, water
at 2.6 GPM/10'' cartridge. Contaminants included latex beads,
coarse and fine test dust. Removal efficiencies were determined
using dual laser source particle counters.
Micron ratings from 0.1 to 70 µm– Broad applicationHigh Filtration Efficiency– 90% (Beta 10) Broad chemical compatibility for a wide range of liquid process applications Free of binders, additives and lubricantsFixed pore construction– Eliminates dirt unloading at maximum differential pressureVarious Gasket/O-ring materials– Compatible with many fluids
MS PolyPure Classic Pleated Cartridge Filter®
®
General water and R.O treatment Industrial chemicals and organic solvents Filtration of alcoholic beverages and soft drinks Filtration of various types of process water, including make-up water
Description
Features Filter Removal Efficiency
Applications
Beta Ratio
Efficiency
Beta 10
90%
Beta 5
80%
0.22 micron 0.22 0.1
0.45 micron 0.45 0.22
1.0 micron 1.0 0.45
3.0 micron 3.0 2
5.0 micron 5.0 4
10.0 micron 10.0 6
20.0 micron 20.0 15
30.0 micron 30.0 25
50.0 micron 50.0 30
Address: 1108 Spring View Lane Plano, TX 75075 Toll free: 1-866-528-4572 Fax: 1-732-412-4040RD2PD781C4AE7-EN A/1
MS PolyPure Classic Pleated Cartridge Filter®
Specification Filter Pressure Drop vs .Flowrate
Ordering Information
Address: 1108 Spring View Lane Plano, TX 75075 Toll free: 1-866-528-4572 Fax: 1-732-412-4040
Materials of Construction: · Filter Medium: Polypropylene,· Support/Drainage: Polypropylene· Inner Core: Polypropylene· End caps: Polypropylene· Cage: Polypropylene
Recommended Operating Conditions: · Maximum Operating Temperature: 80℃· Maximum Operating Pressure: 2.4 bar at 20℃· Micron Rating: 0.1μm, 0.22μm, 0.45μm, 1μm, 3μm 5μm,
10μm, 20μm, 30μm, 50μm, 70μm, 100μm· Recommended Change-Out Differential Pressure: 2.4bar
Dimensions:· Outside Diameter: 2.7’’ (6.86 cm)· Inner Diameter: 1.3’’ (3.3 cm)· Length: 9.75’’, 10’’, 20’’, 30’’, 40’’
0 5 10 15 20 25
0
10
20
30
40
Diff
eren
tial P
ress
ure
(mba
r)
Flow Rate (L/min)
Test for 10” FilterUnit conversion: 1bar=100kpa
Flow rate is for a 25.4cm (10inch), cartridge. For liquids other than water,
multiply differential pressure by fluid viscosity (cP)
0.22μm0.45μm1.0μm3.0μm5.0μm
10μm~30μm50μm~100μm
S= Silicon
N= NBR
E= EPDMF=
P= Teflon Encapsulated Viton
Viton
0= DOE
2= 222/Flat
3= 222/Fin
6= 226/Fin
7= 226/Flat
Seal MaterialEnd TypeRemoval Ratings
（μm）Length
（inch）Filter Media
PP= Polypropylene 1000= 10μm
2000= 20μm
3000= 30μm
5000= 50μm
7000= 70μm
10000= 100μm
010= 0.1μm
022= 0.22μm
045= 0.45μm
100= 1μm
300= 3μm
500= 5μm
0975= 9.75”
010= 10”
020= 20”
030= 30”
040= 40”
CRPP
RD2PD781C4AE7-EN A/1
