Fermentation Yeast Extract – More than just a nitrogen source

INNOVATIVE SOLUTIONS FOR BIOTECH APPLICATIONS

EXCELLENCE IN YEAST

Yeast Extracts – What makes them unique?

Yeast extract composition and their benefits

Yeast cell wallBrewers’ yeast cell wall consists of a substantially complex structure containing many interesting and functional components, such as β-1,3- and β-1,6-linked glucan, mannans, mannoproteins, sterols and phospholipids. All these components present a multitude of interesting functions, which serve as versatile tools among others in the field of wine production including clarification, improving fermentation performance and flavoring.

Nucleotides

Minerals &Traces

Carbohydrates& Derivatives

Vitamins &Derivatives

Proteins &free aminoacids

Important growth factors

Metabolic driver

Pace maker of fermentation

Cell protection

Storage compounds

Enzymatic cofactors

Building blocks for biosynthesis

Supply of nitrogen

Cell protection against stress,osmotic pressure, free radicals

Essential enzymatic cofactorsfor biocatalytic activities

Impacting and regulatingintracellular transport processes

Maintaining electrical potential viamembranes

In the complex world of biotechnology and fermen-tation, Leiber brewers’ yeast extracts have proven to be more than just a nitrogen source! Yeast extracts have a long tradition in the fermentation industry, serving as a nutritious and effective complex nit-rogen source for a broad spectrum of production microorganisms belonging to bacteria, fungi and yeasts.The production of beer, and thus the production of the by-product brewers’ yeasts is carried out mainly on the basis of renewable, natural raw materials such as barley, hops and water. The solids, including mainly the yeast biomass, remain in the tank as by-

product. Yeast extract from brewers’ yeast is charac-terized by a high sustainability and thus the manu-facturing can be regarded as ecologically valuable and efficient.

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Brewers’ yeast extracts in biotech industry

Benefits of using brewers’ yeast extract (e.g. Leiber-Fermentation E) in a vinegar production:

Increased acetic acid yield of up to 80%! Saving 40% of production time! Boosting production capacity! Cost savings! Significantly increased productivity!

Our in-house quality control system ensures top quality of our products. All Leiber fermentation products comply with the requirements of VLOG certification: A GMO free certification based on EGGenTDurchfG.

Brewers’ yeast extracts from Leiber have found their way into countless applications, ranging from beverage production and straight forward fermentations for manufacturing of starter cultures, to complex processes of primary and secondary

metabolites production. The possible applications are huge in industrial biotechnology, as well as in the field of fermented food and beverages. It is the perfect choice for applications from lab to big scale industrial fermentation.

Brewers’ yeast extract boosting vinegar production The following study shows the impact of brewers’ yeast extracts applied as nutrient for vinegar production.

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Control: w/o yeast extract +10 g/L yeast extract +20 g/L yeast extract

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Fermentation Yeast Extracts

Well-balanced brewers’ yeast extract

Applications: Bioethanol and biogas fermentation Brewing industry Yeast fermentation Cultivation of starter cultures for meat and dairy Organic acid production

Benefits: Partly debittered Contains a perfectly adjusted concentration of

active hop oils Completely water soluble Light to medium brown powder Kosher & Halal GMO free

Pure and debittered brewers’ yeast extract

Applications: Production of amino and nucleic acids, organic

acids, technical enzymes, unsaturated fatty acids Cultivation of starter cultures for meat and dairy Hormone and vaccine production

Benefits: Well-balanced concentration of free amino acids,

growth promoting vitamins and trace elements Completely water soluble Light beige to light brown powder Kosher & Halal GMO free Gluten-free according to regulation (EU)

No 828/2014

Leiber Fermentation S

Leiber Fermentation E

Product code Product name Consistency

100413 Leiber-Fermentation E Powder

101308 Leiber-Fermentation E, V Paste

100393 Leiber-Fermentation E, L Liquid

Product code Product name Consistency

100431 Leiber-Fermentation S Powder

101099 Leiber-Fermentation S, V Paste

100394 Leiber-Fermentation S, L Liquid

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Fermentation Yeast Extracts

Purified and debittered brewers’ yeast extractRich in amino acids

Applications: Vitamin production Hormone and vaccine production Production of amino and nucleic acids, organic

acids, enzymes and other functional proteins

Benefits: High concentration of valuable free amino acids

and proteins Complex source of nutrition, growth promoting

vitamins and trace elements Completely water soluble Light brown powder Kosher & Halal GMO free Gluten-free according to regulation (EU)

No 828/2014

Brewers’ yeast cell walls

Applications: Clarification of beverages, e.g. wine Reactivation of wine fermentation process

Benefits: Rich in beta-glucan, lipids & mannoproteins Absorb mycotoxins, sterols, polyphenols and

proteins Light tan powder Kosher & Halal GMO free

Leiber Fermentation H

Leiber CeWaFerm®

Product code Product name Consistency

101309 Leiber-CeWaFerm® Powder

Product code Product name Consistency

100434 Leiber-Fermentation H Powder

100395 Leiber-Fermentation H, L Liquid

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Our biotechnological solutions

Process improvements Boosting growth of microorganisms in fermentation Enhancing product synthesis Reduction of fermentation time ⁄ increased profitability Improved productivity and capacity (e.g. acetic acid, ethanol, and more) Clarification of biological solutions, e.g. wine Reactivation of production cells during long lasting fermentation processes

Tailor made yeast extracts in view of: Product composition Grade of protein hydrolysation

Customized products due to your process and specific requirements

Fermentation Yeast Extracts

Leiber – Excellence in Yeast

For more than 60 years Leiber GmbH has been sup-plying high value brewers’ yeast products under the “Made in Germany” banner throughout the world. Their products are used in animal nutrition, food and biotech industry. Using a patented process for drying yeast, Leiber manufactures brewers’ yeast products and yeast extracts of the highest quality standard as its two factories in Germany, and further sites in Poland and Russia.

“The comprehensive know-how about the characteristics of our functional brewers’ yeast extracts combined with our experiences in biotech applications enables Leiber to act as ‘solution provider’ for their customers.”

Dr.-Ing. Guido Melzer,Global Business Development Manager Fermentation

Natural raw materials Modern patented technology Quality products “Made in Germany“ Leiber brewers’ yeast products are not

genetically modified Individual scientific advice Leiber is ISO 22000:2005, FSSC 22000,

IFS and VLOG certified Kosher & Halal

Yeast extracts are common products made by extracting the cell contents (removing the cell walls). They are used as complex nutrients for culture media for fermentation applications.

Why yeast extract for fermentation?

Yeast extracts are essential nutrients for

production organisms deliver nitrogen in form of

proteins and amino acids deliver vitamins, minerals and

traces as important cofactors and stimulants deliver nucleotides as important

growth factors

Leiber GmbHHafenstraße 2449565 BramscheGermany

Tel. +49 (0) 5461 9303-0Fax +49 (0) 5461 9303-5033www.leibergmbh.defoodsales@leibergmbh.de