DERMSCAN NEWS€¦ · The effecTs of air polluTion on skin (indusTry, heaTing, TransporT) producT...

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PARAMETERS DECREASING Cellular renewal Moisturization Vitamin E Squalen (in sebum) pH ATP (in stratum corneum) IL1α (in stratum corneum) Collagen synthesis Tissular oxygenation Suppleness Chymotrysin like activity Skin radiance Treated zone (Hair locks) Untreated zone (Hair locks) www.dermscan.com Treated zone (forearm) Untreated zone (forearm) PARAMETERS INCREASING TEWL Lactic acid Oxidative stress Oxidized squalen (in sebum) Wrinkles (nasolabial folds) Pigment spots Carbonylated proteins (in stratum corneum) Heavy metals and/ or dusts deposits Roughness Inflammatory reactions, Sensitivity, reactivity Dull skin BEFORE cleansing AFTER cleansing Consequently, the skin and scalp are irritated, more reactive and more sensitive. THE EFFECTS OF AIR POLLUTION ON SKIN (INDUSTRY, HEATING, TRANSPORT) PRODUCT EFFECTIVENESS MEASUREMENTS Dermscan provides advice on the most relevant parameters to be measured according to the expected efficacy of your products. We offer protocols for skin or hair for laboratory use (deposition of fine particles) or for use in a polluted urban environment. DERMSCAN NEWS ANTI-POLLUTION PRODUCTS IN VIVO MEASUREMENT OF TISSUE OXYGENATION: Evaluation of protective effect against cutaneous hypoxia caused by pollution, through transcutaneous measurement of partial pressure of O2 and CO2. IN VIVO MEASUREMENT OF PROTECTIVE OR CLEANSING EFFECT AGAINST POLLUTION PARTICULES: Protective or cleansing effect for topical product. Cleansing effect for hair product. Laboratoire Dermscan: +33(0) 472 823 658 or [email protected] Pharmascan: +33(0) 472 823 651 or [email protected] For more information on the Dermscan Group: EXAMPLE OF PROPOSED TESTS Skin oxygenation (tcpO 2 ) before, then 4 h and 24 h after application of an anti-pollution product Repeated exposure to pollution causes significant changes to skin parameters as: (mm Hg)

Transcript of DERMSCAN NEWS€¦ · The effecTs of air polluTion on skin (indusTry, heaTing, TransporT) producT...

Page 1: DERMSCAN NEWS€¦ · The effecTs of air polluTion on skin (indusTry, heaTing, TransporT) producT effecTiveness measuremenTs Dermscan provides advice on the most relevant parameters

PARAMETERS DECREASING

Cellular renewal Moisturization

Vitamin E Squalen (in sebum)

pHATP

(in stratum corneum)

IL1α (in stratum corneum)

Collagen synthesis

Tissular oxygenation Suppleness

Chymotrysin like activity Skin radiance

Treated zone(Hair locks)

Untreated zone(Hair locks)

www.dermscan.com

Treated zone (forearm)

Untreated zone

(forearm)

PARAMETERS INCREASING

TEWL Lactic acid

Oxidative stress Oxidized squalen (in sebum)

Wrinkles (nasolabial folds) Pigment spots

Carbonylated proteins (in

stratum corneum)

Heavy metals and/or dusts deposits

Roughness Inflammatory reactions,

Sensitivity, reactivity Dull skin

BEFORE cleansing AFTER cleansing

Consequently, the skin and scalp are irritated, more reactive and more sensitive.

The effecTs of air polluTion on skin (indusTry, heaTing, TransporT)

producT effecTiveness measuremenTs

Dermscan provides advice on the most relevant parameters to be measured according to the expected efficacy of your products. We offer protocols for skin or hair for laboratory use (deposition of fine particles) or for use in a polluted urban environment.

DERMSCAN NEWS anTi-polluTion producTs

in vivo measuremenT of Tissue oxygenaTion: Evaluation of protective effect against cutaneous hypoxia caused by pollution, through transcutaneous measurement of partial pressure of O2 and CO2.

in vivo measuremenT of proTecTive or cleansing effecT againsT polluTion parTicules:

Protective or cleansing effect for topical product.

Cleansing effect for hair product.

laboratoire dermscan: +33(0) 472 823 658 or [email protected]

pharmascan: +33(0) 472 823 651 or [email protected]

For more information on the Dermscan Group:

example of proposed TesTs

skin oxygenation (tcpo2) before, then 4 h and 24 h after application of an anti-pollution product

Repeated exposure to pollution causes significant changes to skin parameters as:

(mm

Hg

)