Cardiovascular events and CKD Cardiorenal syndrome · Anemia, CKD and CHF Commonly Appear Together...
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Cardiovascular events and CKD Cardiorenal syndrome Ιωάννης Γ. Γριβέας,MD,PhD
Transcript of Cardiovascular events and CKD Cardiorenal syndrome · Anemia, CKD and CHF Commonly Appear Together...
Cardiovascular events and CKD
Cardiorenal syndrome
Ιωάννης Γ. Γριβέας,MD,PhD
BIG
CONCEPTBring the attention of your audience
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“There are good grounds
but by no means a proven
case for suspecting excess
salt intake, probably
associated with reduced
potassium intake , in the
aetiology of hypetensionn
in Western-Type
communities “
RENAL SODIUM RETENTION
Pressure
Natriuresis
Ischemic
nephron-Reduced
Nephron number
Quabain
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…Η Μοριακήβιολογία τουσυστήματος είναιπιο περίπλοκηαπό ότιπιστεύαμε…
…Human reningene…
ΠΙΘΑΝΈΣ ΕΞΗΓΉΣΕΙΣ…
Ischemic nephrons
Increased
sympathetic drive
Defective
feedback
regulation of
the RAAS in the kidney
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Εξήγηση του φαινομένου
Abnormally regulated and rather fixed local level of tissue AII
ABNORMAL MODULATION
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