CARDIOVASCULAR DRUGS

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2. . x .shock . x . 3. 4. DOPAMINE DOBUTAMINE ADRENALINE NORADRENALINE MILRINONE 5. CH 2 CH 2 NH 2 C H OH NH CH 3 6. CH 2 CH 2 NH 2 C CH 2 NH 2 H OH C CH 2 NH H OH CH 3 7. tyrosine L-dopa dopamine nordrenaline 8. catecholamines 9. 1 2 1 2 DA D 1 D 2 G AMP ( IP 3 ) Ca - K 10. DA 11. 1 2 1 2 DA D 1 D 2 -- --- , - 12. - 2min 5min 13. - 1 1 D 1 - - D 1> 1> 1 10 2 . ( SVR ) 14. - 15. - - P O 2 SVR ARDS 27% 40%. 16. - - - 17. Surviving Sepsis Campaign Sepsis Occurrence in Acutely ill Patiens SOAP study 18. 2min 1 2 min - 19. - 1> 2> 1-20 / kg/min 1 2 1> 2 < 10 - > > 10 . ( SVR ) .. 2 20. - - 21. 1-2min 22. - . ( SVR ) 1 () 23. - 24. - .. 2 25. - 26. 1-2min 27. - 1 > 2 , . . 0,1 2 / kg/min > 0,2 28. - shock shock 29. - 30. - cAMP 0,375 kg/min 0,750 /kg/min 31. - 32. - SVR CVP PCWP 33. - DOWN REGULATION OXI 34. DOWN REGULATION 35. - SVR ;; 36. - Rebound ARREST 37. monitoring 38.