Adrenergic agonist drugs Objectives Discuss the pharmacology of catecholamines Classify &...

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Transcript of Adrenergic agonist drugs Objectives Discuss the pharmacology of catecholamines Classify &...

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Adrenergic agonist drugsObjectives

Discuss the pharmacology of catecholaminesClassify & describe adrenergic -agonists including actions, therapeutic uses & adversereactions.

Classify & describe adrenergic -agonists including actions, therapeutic uses & adversereactionsAdrenergic transmission

Catacholamines - Epinephrine (1212),Norepinephrine(121), Isoproterenol (12)

Adrenaline- 1 2 1 2

ADR-Other catecholaminesNoradrenaline (1 2 1 ) is used in severe shockNA adverse effects are similat to adrenaline. In addition NA causes severe sloughing of skin due vasoconstriction Dobutamine(1) is preferred in Acute congestive heart failure

Dopamine- (, 1, D ) -used in cardiogenic & septic shock-

Therapeutic classification of adrenergic drugs

Ephedrine

Phenylepherine

Nasal decongestants

Amphetamine

Anorectics

Clonidine

2 adrenergic agonist

Uterine relaxants

Summary of Sympathomimmetics - agonist

Summary of - Agonists

References- Lippincotts Illustrated pharmacologyKatzung Basic & Clinical Pharmacology