5 - Implementing Hydrobiology Methods in LabWare - Imraan ... · Microsoft PowerPoint - 5 -...

Rand WaterImplementing methods in a Implementing methods in a

Hydrobiology Lab – Chlorophyll-α and Chlorophyll 665Chlorophyll-665

Presented by:I P bh iImraan Peerbhai

10 September 2013

Presentation Outline1. Rand Water - Background2. Who is Analytical Services?3. Why Chlorophyll-α and 665?4. Process followed5 Challenges experienced5. Challenges experienced6. Screenshots of system7 Benefits to the lab7. Benefits to the lab8. Lessons learned9. Conclusion & way forwardy

Rand Water - Background

• So who is Rand Water exactly?

• What do they do?

• Who are the customers?

• What area is covered?

• Where does the water come from?

Rand Water – Background contd..

• How is the water treated?

• What about during the pumping process?

• How often are samples taken?

• Are there standards that you adhere to?

Analytical Services

• Division within Scientific Services - part of the Operating P tf li t d b I f ti M tPortfolio – supported by Information Management

• Some numbers (month of March) :• Some numbers (month of March) : • Sampling points – 1 129• Samples taken – 22 289p• Analyses performed – 86 095• Results – 455 589• Instruments interfaced - 113

Chlorophyll-α and Chlorophyll-665

• Significance of the Chlorophyll analysis

• Algal related water problems : Algae interferes with the purification process• Algae interferes with the purification process

• Algae results in water with bad taste, odour and colour• Trihalomethane pre-cursor and source of carbon forTrihalomethane pre cursor and source of carbon for

microbiological growth

Process Followed

• Compilation of URD’s

• System development

• Testing and training

• Rollout to production

Challenges

• Interfacing instruments

• Design – multiple options during brainstorming

• Linking reference monthly QC’s to daily batches

• Viewing of multiple components in a chart

Challenges

• Pipettes

• The design of specification limits for pipettes had to accommodate the following requirements

• Pipettes are method specific

• Pipettes are categorised by volume

• Each pipette has limits for 10%, 50% and 100% of its capacity

PTS and IAC• PTS = Proficiency Testing Scheme

• IAC = Inter-Analyst CompetencyIAC Inter Analyst Competency

• Rand Water runs the PTS (and internal IAC) for Chlorophyll-α and Chlorophyll 665

M l i E l > L bW i E l• Manual process using Excel -> LabWare using Excel

PTS and IAC

PTS and IAC

• Workflow:

PTS and IAC

Example User Interface• Batch creation

Example User Interface• Create duplicate

Example User Interface• Assigning samples to wells (Eliza - Microcystin)

Benefits Realised• Ensuring QC’s done and comply to Quality manual – Stops

the process until all pre-requisites are completed

• Reduced amount of time spent on data entry

• Higher accuracy of data – finger faults eliminatedHigher accuracy of data finger faults eliminated

• All necessary QC’s included in the batch

• Flagging out-of-spec data

• Free up analysts to perform other lab tasksp y p

Lessons Learned

• Thorough analysis of requirements before design is critical

• Design improved with every method implemented

• Thorough analysis and design improves• Thorough analysis and design improves

ease of use of solution for user

maintenance in future

The Way Forward

• Continuous improvement of analysis and design t h itechniques

• Implement using built-in LabWare functionality or modules h iblwhere possible

• Accept that, sometimes (often, actually), LIMS Basic d l t i i it bl d t i b i ldevelopment is inevitable due to unique business rules

• Implement Plate Manager module and Enhanced Visual Workflows

THANK YOUTHANK YOU

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