Γεώργιος Ντάιος Παθολογική Κλινική & Ομώνυμο...

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Αντιθρομβωτική αγωγή σε ασθενή με αγγειακό εγκεφαλικό επεισόδιο. Γεώργιος Ντάιος Παθολογική Κλινική & Ομώνυμο Ερευνητικό Εργαστήριο Ιατρική Σχολή, Πανεπιστήμιο Θεσσαλίας. Καβάλα 28/09/2013. Disclosures. - PowerPoint PPT Presentation

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28/09/2013DisclosuresSupport to attend conferences: Bayer; Sanofi-Aventis; Pfizer; Lundbeck; Boehringer-Ingelheim; Galenica; Elpen; Bristol Myers Squibb.

Honoraria: Quintiles; CHUV; Medtronic.

Speaker fees: Sanofi

Scholarships: European Stroke Organization; Hellenic Society of Atherosclerosis.

Participation in trialsNational coordinator (Greece) for the ENOS trial.Sub-investigator (AMGEN, 20110118).

1 , ; per osLMWH ;

Bath PM, et al. Stroke. 2000;31:1770-1778

Bath PM, et al. Stroke. 2000;31:1770-1778 , ; per osLMWH ; 2 , ;/ / IIb/IIIa inhibitorsCochrane Database of Systematic Reviews 2008; 3: CD000029Aspirin vs. control in acute ischemic stroke: recurrence

13Aspirin vs. control in acute ischemic stroke: death or dependence Cochrane Database of Systematic Reviews 2008; 3: CD000029

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N Engl J Med 2013; 369:11-9

N Engl J Med 2013; 369:11-9

N Engl J Med 2013; 369:11-9

N Engl J Med 2013; 369:11-918 , ;/ / IIb/IIIa inhibitors

LA diameter: 38mmHolter : (-) 3 , ; per osTOAST classification

24 4 , ;/ / IIb/IIIa inhibitorsLancet 2009; 373: 184960Aspirin

26DipyridamoleChen ZM, et al. Stroke. 2000; 31:1240-9

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Aspirin/dipyridamole vs. Aspirin: stroke recurrenceStroke 2008;39;1358-136328Lancet 1996; 348: 132939CAPRIE: Clopidogrel vs. aspirin

29CAPRIE: Clopidogrel vs. aspirinLancet 1996; 348: 132939

30PROFESS: Clopidogrel vs. aspirin/dipyridamoleN Engl J Med 2008;359:1238-51

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TriflusalTACIP: Triflusal vs. Aspirin

Matias et al. Stroke 2003;34:840-84833

TACIP: Triflusal vs. AspirinMatias et al. Stroke 2003;34:840-84834MATCH Primary end point (Stroke, MI, death)Lancet 2004; 364: 33137

35MATCH ICH ratesLancet 2004; 364: 33137

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CHARISMA: Clopidogrel/aspirin vs. aspirinN Engl J Med 2006;354:1706-1737 4 , ;/ / IIb/IIIa inhibitorsAHA guidelinesStroke 2011;42:31-98

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