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, , : . , . () . . 60 . 329 (LBI, , , 2002). , , . , . 1963 .

(), 12,6 500.000 (NHLBI, 2002). (orth, 2002). . , , ( ), , , . . , , 3,3% . , . , . (NHLBI, 2002). ,

. . , 45 . . 10 , . , . . , . Framingham ( 29-1). , . , , . ( 29-1). . 65 . 80% . , . . A , . . . . . , . , . ,

, , . 140 mmHg 90 mmHg. , 1/3 50 . , . (NHLBI, 2002). () . - . , , . , . . . (LDL) . LDL , . 29-2 LDL . , HDL , . HDL 35 mg/dL . , , (VLDL). . . , , . . . . : , , , . . , (HRT). , HDL LDL , . ( ) (). 35 , .

. , , , . , , (Woods, Froelicher, & Motzer, 2000). H Womens Health Initiative (Writing Group, 2002). (. ) , , , (), HRT. (Woods et al., 2000). , . , , . 30% (Woods et al., 2000). . , . , , , . ( ). , DL , . ( >30%), () . , . Framingham, 50 10% . , , . . 0,8 () 0,9 () . . . , , . , , , .

, . , , . , , , , -3 , , (ational Cholesterol Education Program, 2001). , , , . , . . . . . (. 28-4). , . ( ), , . , . , (Porth, 2002). . ( ) . . , . . , . , . , . ,

. , , . , . . , . . , . , , , , , . , . , . , , , . 75% . , . (Copstead & Banasik, 2000). . 29-3 . () . , , . . . , , (McCance & Huether, 2002). (). , . , . . .

. , , . , ( LDL HDL). . , HDL LDL, HDL . 1:5, 1:3. (. 29-2). , 3 , 10 12 . . () . C- . . - (ankle-brachial blood pressure index - ) , . . . ( ST 3 mm . 29-1), , , . (electron beam computed tomography - EBCT) , . . (. ) , ( ). .

, , , . . 50%, . 3 5 (Woods et al., 2000). E, HDL, LDL . . , . National Cholesterol Education Program (NCEP) , LDL ( 29-4). . , . , . (.. ) trans- , . trans- , . , LDL . , , , -3 ( n-3) , DL , . ( , ) ( , ). 6 12 , . (.. ), (.. , ) . , 6 12. 6 12 . ( ) ( ) DL . , (NCEP, 2001).

. 140 mL , 340 mL 42 mL . . ( ) . . . VLDL, LDL , HDL, . , 30 5 6 . , . ( 140/90 mmHg) . , , , . . ( ), . , 24. LDL HDL . . LDL. LDL